Based on Shapiro’s recent text, The Art and Science of Mindfulness: Integrating Mindfulness into Psychotherapy and the Helping Professions (2017), the program offers scientific research and meditative practices for therapists interested in awakening the mind and opening the heart. We begin with by defining mindfulness as involving three synergistic elements: intention, attention and attitude. We focus particularly on the attitude of compassion as an essential element of mindfulness and key to its application and practice. We then draw on current research in psychology, medicine and cognitive neuroscience. We will investigate the effects of mindfulness practice on decreasing pathology and increasing positive psychological and physiological states. We will learn about the convergence of neuroscience and mindfulness, and the optimistic message about the brain’s capacity to change. We will identify specific mindfulness practices for both therapist and client, and delve into methods of integrating mindfulness and mindfulness-based therapies into clinical work.